Home Itens selecionados Provedores de dados OAI Créditos Sobre Ajuda

			Busca avançada
	Provedor de dados BJPS (1) Autor Barbosa,Raquel de Melo (1) Fernandes,Marcelo Augusto Costa (1) Finkler,Christine Lamenha Luna (1) Finkler,Leandro (1) Pereira,Ana Karina Vidal (1) Palavra-chave Artificial Neural Networks (1) Liposomes (1) Local anesthetics (1) Response Surface Methodology (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2020 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Comparative analyses of response surface methodology and artificial neural networks on incorporating tetracaine into liposomes BJPS Pereira,Ana Karina Vidal; Barbosa,Raquel de Melo; Fernandes,Marcelo Augusto Costa; Finkler,Leandro; Finkler,Christine Lamenha Luna. This study evaluated the incorporation of tetracaine into liposomes by RSM (Response Surface Methodology) and ANN (Artificial Neural Networks) based models. RCCD (rotational central composite design) and ANN were performed to optimize the sonication conditions of particles containing 100 % lipid. Laser light scattering was used to perform measure hydrodynamic radius and size distribution of vesicles. The liposomal formulations were analyzed by incorporating the drug into the hydrophilic phase or the lipophilic phase. RCCD and ANN were conducted, having the lipid/cholesterol ratio and concentration of tetracaine as variables investigated and, the encapsulation efficiency and mean diameter of the vesicles as response variables. The optimum sonication... Tipo: Info:eu-repo/semantics/article Palavras-chave: Local anesthetics; Liposomes; Response Surface Methodology; Artificial Neural Networks. Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100517 Registros recuperados: 1 Primeira ... 1 ... Última

Empresa Brasileira de Pesquisa Agropecuária - Embrapa Todos os direitos reservados, conforme Lei n° 9.610 Política de Privacidade Área restrita		Embrapa Parque Estação Biológica - PqEB s/n° Brasília, DF - Brasil - CEP 70770-901 Fone: (61) 3448-4433 - Fax: (61) 3448-4890 / 3448-4891 SAC: https://www.embrapa.br/fale-conosco